Prevalence and per-act risk are different numbers

Two numbers decide your risk from one sexual encounter with someone whose HIV status you don’t know:

  1. Prevalence: the share of adults in a place who have HIV. The figures here are UNAIDS estimates for adults aged 15 to 49. For a few countries without one, such as the US, the calculator uses approximate national figures.
  2. Per-act risk: the chance HIV passes on in one act if your partner does have HIV and isn’t on effective treatment. For insertive vaginal sex, CDC estimates this at 0.04% (about 1 in 2,500).

Your overall risk is roughly the first multiplied by the second. That’s why the numbers in the tables below are so much smaller than the per-act risks you may have read about elsewhere.

Treatment changes the picture

A person with HIV who keeps an undetectable viral load on treatment doesn’t pass HIV on through sex. This is known as U=U. So what matters isn’t only how many people have HIV, but how many of them are on treatment and virally suppressed.

Worldwide, WHO reports that at the end of 2025 about 41.0 million people were living with HIV. Of them, 88% knew their status, 89% of those were on treatment, and 95% of those on treatment had a suppressed viral load. Coverage varies a lot between countries, and the tables take each country’s own treatment coverage into account.

Single-act risk with a partner of unknown status

Each table shows the estimated risk from one act of insertive vaginal sex without a condom (a man with a woman) with a partner whose status is unknown, using that country’s prevalence and treatment data.

The Americas

Chance of HIV from one exposure to a partner of unknown status
CountryRisk per exposureOdds
United States<0.0001%1 in 1,500,000
Canada<0.0001%1 in 16,000,000
Mexico<0.0001%1 in 3,600,000
Brazil<0.0001%1 in 1,700,000
Argentina<0.0001%1 in 3,300,000
Colombia<0.0001%1 in 3,000,000
Jamaica0.00021%1 in 470,000
Haiti0.00015%1 in 660,000

Europe

Chance of HIV from one exposure to a partner of unknown status
CountryRisk per exposureOdds
United Kingdom<0.0001%1 in 15,000,000
Ireland<0.0001%1 in 22,000,000
France<0.0001%1 in 8,000,000
Germany<0.0001%1 in 23,000,000
Spain<0.0001%1 in 15,000,000
Italy<0.0001%1 in 8,000,000
Netherlands<0.0001%1 in 39,000,000
Portugal<0.0001%1 in 3,600,000
Poland<0.0001%1 in 2,500,000
Ukraine0.0004%1 in 250,000
Russia0.00048%1 in 210,000

Asia and the Pacific

Chance of HIV from one exposure to a partner of unknown status
CountryRisk per exposureOdds
India<0.0001%1 in 4,200,000
China<0.0001%1 in 2,500,000
Japan<0.0001%1 in 12,000,000
Thailand<0.0001%1 in 1,700,000
Vietnam<0.0001%1 in 3,500,000
Philippines<0.0001%1 in 9,300,000
Indonesia<0.0001%1 in 1,500,000
Pakistan<0.0001%1 in 4,200,000
Australia<0.0001%1 in 50,000,000

Africa and the Middle East

Chance of HIV from one exposure to a partner of unknown status
CountryRisk per exposureOdds
Egypt<0.0001%1 in 12,000,000
Morocco<0.0001%1 in 11,000,000
Nigeria0.00014%1 in 710,000
Ghana0.00047%1 in 210,000
Cameroon0.00024%1 in 420,000
Ethiopia<0.0001%1 in 1,500,000
Kenya0.0003%1 in 330,000
Uganda0.00052%1 in 190,000
Tanzania0.00035%1 in 280,000
Mozambique0.0014%1 in 70,000
Zimbabwe0.00055%1 in 180,000
South Africa0.0023%1 in 44,000
Botswana0.00091%1 in 110,000
Eswatini0.0014%1 in 69,000

Regional averages

Chance of HIV from one exposure to a partner of unknown status
CountryRisk per exposureOdds
World average<0.0001%1 in 1,200,000
Sub-Saharan Africa0.00035%1 in 280,000
Eastern and Southern Africa0.00046%1 in 220,000
Western and Central Africa0.00018%1 in 570,000
Latin America and the Caribbean<0.0001%1 in 1,300,000
South Asia<0.0001%1 in 5,300,000
Middle East and North Africa<0.0001%1 in 4,300,000

For receptive vaginal sex (a woman with a man), the per-act risk is higher. In the United States, for example, the estimate with a partner of unknown status is 0.00014% (about 1 in 730,000), and in South Africa it’s 0.0023% (about 1 in 44,000). Full tables for every type of sex are on the risk tables page.

Where HIV is most common

WHO reports that 64% of people living with HIV are in the WHO African Region. Prevalence is highest in eastern and southern Africa, where in a few countries a sizeable share of adults have HIV. In much of Western Europe, East Asia and the Middle East, it is well under one percent.

National figures are only a starting point

A country average hides big differences. HIV is more common in some cities, communities and sexual networks than others. CDC links gaps like these to social factors such as poverty, stigma and unequal access to health care. UNAIDS estimates that gay and bisexual men and other men who have sex with men are about 23 times more likely to acquire HIV, and people who inject drugs about 14 times. HIV is also far more common among sex workers and trans women than in the general population.

So for a man having receptive anal sex with another man of unknown status in the United States, the estimate is 0.05% (about 1 in 2,000), higher than the vaginal-sex figures above. The calculator lets you add these details to get a closer estimate.

What the numbers can’t tell you

These are averages. They can’t tell you whether one particular person has HIV. Anyone can have HIV without knowing, especially in the first weeks after infection, when the viral load is highest. A low number is reassuring, but only a test gives you a definite answer.

What to do now

  • Exposed in the last 72 hours, with a partner who has HIV or whose status you don’t know? Ask about PEP (post-exposure prophylaxis) today. It must start within 72 hours and works best within 24. How to get PEP
  • Want a definite answer? Test after the window period. The HIV test accuracy by week page shows when a negative result from each test is conclusive.
  • Want a number for your situation? The calculator combines the country, the type of exposure and any protection you used.